PRX Pharmacy

Nappy rash

Nappy rash is very common in babies and toddlers. It is red, sore skin in the nappy area, caused by contact with wee and poo, friction from the nappy, and sometimes by products that irritate the skin. It usually clears up within a few days with simple care.

Usually clears
Within a few days
Main treatment
Frequent changes and a barrier cream
Avoid
Talcum powder and perfumed products

What it looks like

  • Red, shiny, sore-looking skin on the bottom, genitals and thighs
  • Sometimes small spots or patches, or skin that feels hot
  • Your baby may be upset or cry when the nappy is changed

What you can do

  • Change nappies as soon as they are wet or dirty, and check them often. This is the most important step.
  • Clean gently with warm water and cotton wool or a soft cloth, or fragrance-free, alcohol-free wipes, and pat the skin dry. Do not rub.
  • Apply a thick layer of barrier cream (for example one containing zinc oxide) at every change, to protect the skin.
  • Let your baby go without a nappy for short periods so the skin can air. Lay them on a towel.
  • Do not fasten nappies too tightly.
  • Avoid soap, bubble bath, perfumed products and talcum powder. Talc can be breathed in and is not recommended.
  • Ask us before using any medicated cream. Do not use hydrocortisone in the nappy area without advice.

When it might be thrush

If the rash is bright red, with red spots or patches around the edges that spread into skin folds, or if it has not improved after about a week of good nappy care, it might be a yeast (thrush) infection. This needs an antifungal cream, which a pharmacist can recommend for a baby.

How PRX Pharmacy can help

Our pharmacists can recommend a suitable barrier cream or antifungal treatment for your baby, and show you what to look out for. Just pop in and ask.

When to get medical help

Call 999 or go to A&E if:

  • Your baby is floppy, very drowsy or hard to wake, has a high temperature, or has a rash that does not fade when you press a glass against it

Contact your GP practice or call 111 the same day if:

  • The rash has not improved after about 7 days of good nappy care, or is getting worse
  • The skin is broken, blistered, weeping, crusted or has pus (this may be a bacterial infection)
  • The rash spreads beyond the nappy area
  • Your baby has a fever, or seems unwell
  • The baby is under 4 weeks old
  • The rash keeps coming back

If you are ever worried and unsure, ask us or call 111. Trust your instincts — it is always better to ask.

This guide is general information written by the PRX Pharmacy team. It does not replace advice from a pharmacist or doctor who knows your medical history.

Last updated 24 September 2026. Clinically reviewed by Milan Patel, Pharmacist on 24 September 2026.

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